Dmpk CLIA Kit for Mouse(Mus musculus) | EIAab.comDmpk CLIA Kit for Mouse(Mus musculus)

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Index > Protein center > Dmpk(Gene name) > Mouse

Dmpk (Gene name),

Myotonin-protein kinase (Protein name ), DMPK_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Dmpk(Dm15;Mdpk);

Protein name:

Myotonin-protein kinase(MT-PK);

Alternative:

DMPK;DM-kinase(DMK);Myotonic dystrophy protein kinase(MDPK);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer.

Function:

Critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity. Phosphorylates phospholamban.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

631

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

631:

AAAATLGCTG | LVAYTGGLTP | VWCFPGATFA | P

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000032568

SMR:

P54265

UniGene:

Mm.6529

String:

P54265

Pfam:

PF08826

KEGG:

mmu:13400

Uniprot:

P54265

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ELISA Kit for Mouse MT-PK

Cat.:

E15231m

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse MT-PK

Cat.:

E15231h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MT-PK

Cat.:

U15231h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MT-PK

Cat.:

U15231m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse MT-PK

Cat.:

P15231Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MT-PK

Cat.:

P15231Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse MT-PK

Protein for Mouse MT-PK

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene."
Mahadevan M.S. , Amemiya C. , Jansen G. , Sabourin L. , Baird S. , Neville C.E. , Wormskamp N. , Segers B. , Batzer M. , Lamerdin J. , de Jong P.J. , Wieringa B. , Korneluk R.G.
Hum. Mol. Genet.2:299-304(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"No imprinting involved in the expression of DM-kinase mRNAs in mouse and human tissues."
Jansen G. , Bartolomei M. , Kalscheuer V. , Merkx G. , Wormskamp N. , Mariman E. , Smeets D. , Ropers H.-H. , Wieringa B.
Hum. Mol. Genet.2:1221-1227(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129/Sv.
3.

"Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs."
Jansen G. , Mahadevan M.S. , Amemiya C. , Wormskamp N. , Segers B. , Hendriks W. , O'Hoy K. , Baird S. , Sabourin L. , Lennon G. , Jap P.L. , Iles D. , Coerwinkel M. , Hofker M. , Carrano A.V. , de Jong P.J. , Korneluk R.G. , Wieringa B.
Nat. Genet.1:261-266(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 117-631 (ISOFORMS 2; 4; 5 AND 8)
tissue: Brain.
4.

"Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy."
Reddy S. , Smith D.B. , Rich M.M. , Leferovich J.M. , Reilly P. , Davis B.M. , Tran K. , Rayburn H. , Bronson R. , Cros D. , Balice-Gordon R.J. , Housman D.
Nat. Genet.13:325-335(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
5.

"Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cells."
Benders A.A. , Groenen P.J. , Oerlemans F.T. , Veerkamp J.H. , Wieringa B.
J. Clin. Invest.100:1440-1447(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELLULAR CALCIUM HOMEOSTASIS
6.

"Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties."
Groenen P.J.T.A. , Wansink D.G. , Coerwinkel M. , van den Broek W. , Jansen G. , Wieringa B.
Hum. Mol. Genet.9:605-616(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 1; 3; 5; 6; 8 AND 9)
7.

"Progressive atrioventricular conduction block in a mouse myotonic dystrophy model."
Berul C.I. , Maguire C.T. , Gehrmann J. , Reddy S.
J. Interv. Card. Electrophysiol.4:351-358(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
8.

"A role for myotonic dystrophy protein kinase in synaptic plasticity."
Schulz P.E. , McIntosh A.D. , Kasten M.R. , Wieringa B. , Epstein H.F.
J. Neurophysiol.89:1177-1186(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN SYNAPTIC PLASTICITY
9.

"Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum."
Kaliman P. , Catalucci D. , Lam J.T. , Kondo R. , Gutierrez J.C. , Reddy S. , Palacin M. , Zorzano A. , Chien K.R. , Ruiz-Lozano P.
J. Biol. Chem.280:8016-8021(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CALCIUM UPTAKE BY CARDIAC SARCOPLASMIC RETICULUM;FUNCTION IN PHOSPHORYLATION OF PLN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
10.

"Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors."
van Herpen R.E. , Oude Ophuis R.J. , Wijers M. , Bennink M.B. , van de Loo F.A. , Fransen J. , Wieringa B. , Wansink D.G.
Mol. Cell. Biol.25:1402-1414(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBCELLULAR LOCATION;TOPOLOGY;AUTOPHOSPHORYLATION
11.

"Myotonic dystrophy protein kinase is expressed in embryonic myocytes and is required for myotube formation."
Harmon E.B. , Harmon M.L. , Larsen T.D. , Paulson A.F. , Perryman M.B.
Dev. Dyn.237:2353-2366(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MYOGENESIS;SUBCELLULAR LOCATION
12.

"Myotonic dystrophy protein kinase is critical for nuclear envelope integrity."
Harmon E.B. , Harmon M.L. , Larsen T.D. , Yang J. , Glasford J.W. , Perryman M.B.
J. Biol. Chem.286:40296-40306(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NUCLEAR ENVELOPE STABILITY;SUBCELLULAR LOCATION

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